Figure 3.

The chlamydial developmental cycle and persistence induction and reactivation using IFN-γ and carbenicillin. (A) Samples were collected for northern blotting at the times indicated (IFN, IFN-γ persistence; IFN R, IFN-γ reactivation; Cb, carbenicllin persistence; Cb R, carbenicillin reactivation). (B) Titers of samples collected at 48 h PI for each of the experiments (indicated by the asterisks next to time points in Figure 4A). Both persistence induction conditions resulted in significant reductions in IFUs at 48 h PI which returned to near normal IFU numbers following reactivation.