Figure 1.

Alignment of PHD fingers from the N-terminal extended alignment. Five positions N-terminal to Cys¹ are shown. Zinc ligand positions are shown as gray boxes. Sequences are grouped according to their family assignment by our method (Table 1), with first-percentile conditions satisfied indicated in bold, and conditions originating from a family different from the one the sequence was assigned to in bold and italics. Sequences named without a suffix are from human. Those terminated with AT, CA, SP and Y are respectively from Arabidopsis thaliana, Candida albicans, Schizosaccharomyces pombe and Saccharomyces cerevisiae. Many of these sequences were not present in the initial (non-extended) CD-Hit-filtered alignment, and were thus not used for the determination of the families of conditions, but were added here as being better described in the literature.