Figure 5.
Comparison of our best-fit results with other anthrax models when modelling risk for a single bolus dose. To calculate this risk when α = 0.9, equations (2.6) and (2.9) were used in combination with MLE values, s = 1.81 × 10−7 h−1 and γ = 0.001 h−1. When α = 1, our model is equivalent to an exponential model with k = s/γ = 3.57 × 10−5. Previous exponential modelling of Brachman data assuming each day as an independent dosing event yielded k = 2.4 × 10−5 [15]. A model of anthrax outbreak in Rhesus monkeys which included clearance rate and hazard rate yielded an attack rate formula equivalent to an exponential model with k = 7.17 × 10−5 [10]. Thick line, Brachman results 
; dashed line, Brachman results α = 1; dash-dotted line, Brachman results [15]; dotted line, Brookmeyer et al. [10].