Table 1.
Some Reported Interventional Strategies Aimed at Increasing Life Span
| Factor | Organism/cell origin | Life span extension (yes/no) | References |
|---|---|---|---|
| Exercise | Mus musculus | No | 321 |
| Rattus norvegicus | Yes | 148 | |
| Heat shock | Caenorhabditis elegans | Yes | 209 |
| Drosophila melanogaster | Yes | 172 | |
| Mild repeated heat shock | Human cells | No | 387 |
| Vitamin C | Human cells | Yes | 167 |
| Tea extract | D. melanogaster | Yes | 227 |
| N-acetyl cysteine | D. melanogaster | Yes | 33 |
| N-t-butyl hydroxylamine | Human cells | Yes | 18 |
| Resveratrol | Saccharomyces cereviseae | Yes | 149 |
| Rapamycin | Outbred mice | Yes | 137 |
| Spermidine | Human peripheral blood mononuclear cell | Yes | 88 |
| Caloric restriction | M. musculus | Yes | 183, 395 |
| Homo sapiens | Not assessed | 392 |