Table 2.
Pulmonary function & clinical characteristics of BOS patients at time of meeting NIH criteria based upon clinical recognition status
Measure | Concurrent n = 38 | Late n = 14 | Unrecognized n = 11 | p-value* | All Cases N = 63 | ||||
---|---|---|---|---|---|---|---|---|---|
Median | Range | Median | Range | Median | Range | Median | Range | ||
FEV1 (%) | 58% | (16%, 74%) | 57% | (38%, 74%) | 64% | (44%, 73%) | 0.1750 | 59% | (16%, 74%) |
SVC (%) | 73% | (41%, 99%) | 72% | (46%, 97%) | 75% | (57%, 91%) | 0.5871 | 73% | (41, 99%) |
FEV1/SVC ratio | 0.61 | (0.29, 0.69) | 0.58 | (0.46, 0.68) | 0.64 | (0.54, 0.69) | 0.0646 | 0.63 | (0.29, 0.69) |
TLC (%) | 99% | (75%, 153%) | 96% | (64%, 120%) | 90% | (66%, 119%) | 0.3360 | 96% | (64, 153%) |
RV (%) | 155% | (65%, 334%) | 113% | (62%, 195%) | 116% | (57%, 163%) | 0.0275 | 135% | (57%, 334%) |
DLCO (%) | 66% | (34%, 95%) | 59% | (9%, 98%) | 60% | (24%, 104%) | 0.2896 | 63% | (9%, 104%) |
LFS | 9 | (4, 12) | 9 | (4, 12) | 8 | (4, 11) | 0.2282 | 9 | (4, 12) |
P-values were calculated using the Kruskal-Wallis test to compare the medians of the concurrent, late, and unrecognized groups.