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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Am J Obstet Gynecol. 2011 Jan 26;204(3):254.e16–254.e28. doi: 10.1016/j.ajog.2010.11.032

Figure 1. Chronic Fetal Hypoxia Results in Selective Anatomic Brain Injury.

Figure 1

Sample photomicrographs from mirror image coronal sections at the interaural level of 6.72mm to 5.40 mm (Bregma: from −2.28 mm to −3.60mm) including cerebral cortex, hippocampus, and thalamic nuclei from hypoxic (n=6) and control fetuses (n=6) stained for ATF3 (10x), GFAB (10x), TUNEL (10x), and Nissl (20x). Chronic hypoxia (10.5% O2 over the last 30% of gestation) visually increases ATF3, GFAB and TUNEL staining with an accompanying decrease in neuronal density.