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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Am J Obstet Gynecol. 2011 Jan 26;204(3):254.e16–254.e28. doi: 10.1016/j.ajog.2010.11.032

Table 2.

Chronic Hypoxia Induces Fetal Brain Injury in Selected Areas

Brain Structure Nuclei Injury Indexes
ATF3 GFAP TUNEL
Cerebral cortex Global wide ++ ++ ++
Hippocampal region cingulum − +++++ −
orices layer hippocampus +++ +++ +++
CA1 + + +
CA2 + + +
CA3 ++++ ++++ ++++
Thalamic nuclei laterodorsal thal nu ++ ++ ++
post thalamic nu + + +
ventrol thalamic nu ++ ++ ++
paraventricular thal nu + + +
mediodorsal thal nu + + +
central thalamic nu ++ ++ ++
reuniens thalamic nu +++ +++ +++
others − − −
Hypothalamic nuclei dorsomed hypothal nu + + +
ventromed hypothal nu + + +
lat hypothal + + +
others + + +