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. Author manuscript; available in PMC: 2012 Apr 1.

Published in final edited form as: Bioorg Med Chem Lett. 2011 Feb 23;21(7):2113–2115. doi: 10.1016/j.bmcl.2011.01.127

Table 1.

HIF-2α inhibitory activity of compounds 1-10

Compound	% HIF Inhibition EC₅₀ (μM)	% Cytotoxicity IC₅₀ (μM)
1	Inactive^a	Inactive^a
2	Inactive^a	Inactive^a
3	107.5	147.3
4	Inactive^a	Inactive^a
5	183.3	291.2
6	Inactive^a	Inactive^a
7	148.9	134.2
8	3.4	5.2
9	6.2	26.3
10	11.8	14.2

^a

>300 μM

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