Skip to main content
. Author manuscript; available in PMC: 2012 Mar 7.
Published in final edited form as: J Immunol Methods. 2011 Jan 19;366(1-2):43–51. doi: 10.1016/j.jim.2011.01.002

Figure 3.

Figure 3

Effect of alternative, non-alanine substitutions in the CDR3α of the HC/2G-1 TCR. Retroviral transduction, co-culture and IFN-γ assay was done as in Figure 1 and 2. WT is the native TCR and parental T-cell clone HC/2Tg-1 was also tested as a positive control. These studies identified AA positions 109 and 112 as loci with augmenting effects on function of this TCR.

HHS Vulnerability Disclosure