Table 2.
Characteristic | Compassionate Use |
All (%) | p-value§ | |
---|---|---|---|---|
No | Yes | |||
Number of Admissions | 5492 | 96 | 5588 | |
Female | 1587 | 32 | 1619 (29) | 0.364 |
Male | 3905 | 64 | 3969 (71) | |
Age < 60 years | 2813 | 37 | 2850 (51) | 0.11 |
61 – 70 years | 1127 | 25 | 1152 (21) | |
71 – 80 years | 976 | 22 | 998 (18) | |
> 80 years | 576 | 12 | 588 (11) | |
Race: White | 4816 | 77 | 4893 (88) | 0.10 |
African American | 140 | 3 | 143 (2.6) | |
Hispanic | 161 | 5 | 166 (3.0) | |
Other | 346 | 11 | 357 (6.4) | |
Previous MI | 937 | 24 | 961 (17) | 0.055 |
No Previous MI | 4555 | 72 | 4627 (83) | |
Diabetes mellitus | 1097 | 33 | 1130 (20) | 0.0012 |
No Diabetes mellitus | 4395 | 63 | 4458 (80) | |
History of Renal Failure | 226 | 15 | 241 (4) | 0.00001 |
No History of Renal Failure | 5266 | 81 | 5347 (96) | |
Previous MI | 937 | 24 | 961 (17) | 0.055 |
No Previous MI | 4555 | 72 | 4627 (83) | |
History of CHF | 311 | 14 | 325 (5.8) | 0.0012 |
No History of CHF | 5181 | 82 | 5263 (94) | |
Cerebrovascular Disease | 374 | 17 | 391 (7) | 0.0003 |
No Cerebrovascular Disease | 5118 | 79 | 5197 (93) | |
Peripheral Vascular Disease | 482 | 17 | 499 (9) | 0.0057 |
No Peripheral Vascular Disease | 5010 | 79 | 5089 (91) | |
Chronic Lung Disease | 586 | 16 | 602 (11) | 0.0672 |
No Chronic Lung Disease | 4906 | 80 | 4986 (89) | |
Hypertension | 3354 | 58 | 3412 (61) | 0.9161 |
No Hypertension | 2138 | 38 | 2176 (39) | |
Current Smoker | 2059 | 33 | 2092 (37) | 0.5952 |
Not a Current Smoker | 3433 | 63 | 3496 (63) | |
Dyslipidemia | 3478 | 48 | 3526 (63) | 0.0101 |
No Dyslipidemia | 2013 | 48 | 2061 (37) | |
Previous PCI | 813 | 9 | 822 (15) | 0.1479 |
No Previous PCI | 4679 | 87 | 4766 (850 | |
Previous CABG | 248 | 10 | 258 (5) | 0.0126 |
No Previous CABG | 5244 | 86 | 5330 (95) | |
Current CHF | 834 | 48 | 882 (16) | < 0.00001 |
No Current CHF | 4658 | 48 | 4706 (84) | |
Renal Failure/Dialysis | 39 | 4 | 43 (1) | 0.0060 |
No Renal Failure/Dialysis | 5453) | 92 | 5545 (99) | |
Left Ventricular Ejection Fraction (LVEF) | < 0.00001 | |||
Not Measured | 2858 | 53 | 2911 (52) | |
LVEF < 30% | 433 | 25 | 458 (8.2) | |
31% < LVEF ≤ 40% | 510 | 8 | 518 (9.3) | |
LVEF > 40% | 1691 | 10 | 1701 (30) | |
Cardiogenic Shock | 394 | 63 | 457 (8) | < 0.00001 |
No Cardiogenic Shock | 5098 | 33 | 5131 (92) | |
STEMI | 5175 | 80 | 5255 (94) | 0.00015 |
No STEMI | 317 | 16 | 333 (6) | |
Status of PCI | ||||
Elective/Urgent | 332 | 1 | 333 (6) | < 0.00001 |
Emergent | 5143 | 60 | 5203 (93) | |
Salvage | 17 | 35 | 52 (1) | |
Presence of LMCA lesion | 268 | 76 | 5300 (95) | < 0.00001 |
No LMCA lesion | 5224 | 20 | 288 (5.2) | |
Intra-Aortic Balloon Pump | 652 | 47 | 699 (13) | < 0.00001 |
No Intra-Aortic Balloon Pump | 4840 | 49 | 4889 (87) | |
Successful Procedure | 5176 | 76 | 5252 (94) | < 0.00001 |
Unsuccessful Procedure | 316 | 20 | 336 (6) |
All p-values use Fisher’s exact test with the exception of race, ejection fraction, and PCI status which use χ2 tests.
Notes:
MI = myocardial infarction
CHF = congestive heart failure
LMCA = left main coronary artery