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. 2011 Mar;50(2):165–170.

Table 3.

Three cases of T2DM in chimpanzees with clinical history of mean fasting blood glucose and hemoglobin A1c values

Animal Description Year Weight (kg) Mean fasting blood glucose (mg/dL) Mean HbA1c (%) Notes
CB0090 Adult female; born 1 Jan 1971; HIV (+) 2001 58 360 not tested T2DM diagnosed; began glucophage 850 mg twice daily; started high-fiber diet.
2002 48.5 127 not tested Glucophage increased to 1063 mg twice daily.
2003 62 132 not tested Renal cyst found on ultrasound exam.
2004 62 342 10.2 Systemic hypertension diagnosed.
2005 65 135 Glucophage increased to 2000 mg daily. Began glipizide 5 mg daily.
2006 65.5 122 5.3
2007 66 106 5.5
2008 61 121 5.6
2009 61 141 4.6 Slight anemia: A1c perhaps decreased artifactually due to decreased RBC.
2010 58 109 4.7
836 Adult female; born 1 Jan 1971; Hepatitis C (+) 2003 not tested 148
2004 not tested 155 5.9
2005 51.5 144 6.3 T2DM diagnosed; began glucophage 850 mg twice daily.
2006 47 107 6.0
2007 46.5 112 5.6
2008 50 not tested 7.3 Began high-fiber diet.
2009 47.5 140 6.4
2010 45 110 5.6
778 Adult female; born 23 July 1972 2005 not tested not tested not tested T2DM diagnosed; began glucophage 850 mg twice daily.
2006 63.5 118 5.7
2007 64 110 5.6
2008 64.5 116 6.2 Began high-fiber diet.
2009 65.5 139 8.7
2010 66.5 118 6.6 Better control needed—evaluate at next scheduled exam.