Figure 2.
Mucosal humoral anti-OprF response following intramuscular immunization. C57BL/6 mice were immunized with AdC7OprF, AdOprF, Ad5Null or AdC7Null at a dose of 1010 pu/mouse. A. Anti-OprF IgG antibodies in the lung epithelial lining fluid 0, 4, 8 and 12 wk following vector administration. B. Anti-OprF IgGA antibodies in lung epithelial lining fluid 0, 4, 8 and 12 wk following administration. Data are shown as mean ± SEM, n=4 /group, of one of three representative experiments. The dashed line represents the limit of detection. * denotes significance of p<0.05, respectively, between AdC7OprF and Ad5OprF.