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siRNA silencing of JNK3 protects dopaminergic neurons from paraquat and rotenone toxicity. (A, B) At 24 hours after transfection of siRNA, primary cultured E14 mesencephalic neurons were treated with 40 µM paraquat (A), 5 nM rotenone (B), or their respective vehicle control for another 24 hours. The cells were fixed and stained for TH. The number of TH+ neurons was normalized to vehicle control-treated groups. *p < 0.05.
