Figure 7.

Paraquat-induced motor deficits in mice are attenuated by Jnk3 deletion. Jnk3^+/+ and Jnk3^−/− littermates were treated with paraquat (10 mg/kg) or vehicle control saline 2X/week for 6 weeks, and assessed for motor functions. (A) Latency to fall in accelerated rotarod test. (B) Locomotor activity in open field test, quantified as total distance traveled. *p < 0.05; **p < 0.01; n.s. = not significant.