Figure 1.

(A) The nucleotide sequence of the putative promoter region for the human CTRP5 gene. Top: the 1.3-kb fragment (−1322 bp to −29 bp) of the 5′ region of the human CTRP5 gene is shown. The sequence we cloned for the promoter analysis is shown in bold. The TSS, deduced from the 5′ RACE analysis, is located at −62 bp from the start of translation (ATG in red at +1). Predicted promoter regions −1024 bp to −374 bp (pink) and −385 bp to −59 bp (blue). (B) Schematic presentation of the CTRP5 gene located in the 3′ UTR region of MFRP gene. The genomic structure of the MFRP and CTRP5 genes is shown as reported earlier.¹⁷ Exons corresponding to ORF are indicated by closed boxes (1–13) or hatched boxes (b–c), and exons corresponding to UTRs are shown as open boxes. Regions between the exons correspond to introns. The promoter of the CTRP5 is located in its 5′ region.