Fig. 3.

Effect of Oatp inhibitors on the uptake of taurocholate into rat brain after 3-h λ-carrageenan-induced inflammatory pain. Taurocholate accumulation was measured in animals injected with 0.9% saline or 3% λ-carrageenan in the presence of E₁3S (100 μM), digoxin (DK3) (200 μM), fexofenadine (FEX) (100 μM), or bromosulfophthalein (BSP) (1 mM). Results are expressed as mean ± S.D. of six animals per treatment group. Asterisks represent data points that are significantly different from control.