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Effect of diclofenac, a nonsteroidal anti-inflammatory drug, on TGF-β1 concentration in rat serum. Rats were treated with 0.9% saline or 3% λ-carrageenan for 3 h. Diclofenac (30 mg/kg) was injected 15 min after footpad injection. Serum was collected, and TGF-β1 concentration was determined by ELISA analysis. Data points are expressed as mean ± S.D. from nine individual rats. Asterisks represent data points that are significantly different from control.
