Fig. 2.

Frequencies, but not amplitudes, of spontaneous EPSCs are reduced by PGB. A, representative traces of mEPSPs (in the presence of 1 μM TTX) in the absence (top) or presence (bottom) of 500 μM PGB. B and C, mean mEPSC frequencies and amplitudes, respectively. mEPSPs were recorded during 3 min. Mean amplitudes were 39 ± 2 pA in −PGB (n = 11) and 38 ± 2 pA in +PGB (n = 10), whereas frequencies were 1.7 ± 0.4 and 0.5 ± 0.1 Hz, respectively (*, Student's t test, p = 0.004). Values are presented as mean ± S.E.M.