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. 2010 Nov 10;7(3):209–224. doi: 10.1900/RDS.2010.7.209

Figure 1. CXCL10 DNA vaccination in combination with CFA injection effectively reversed hyperglycemia in new-onset diabetic NOD mice.

Figure 1

A, B, C: Time courses of blood glucose levels in NOD mice after the indicated treatments. A: Mice treated with control DNA vaccination plus CFA injection (n = 22). B: Mice treated with CXCL10 DNA vaccination plus CFA injection (n = 26). C: Mice treated with CXCL10 DNA vaccination alone (n = 10). D: Kaplan-Meier plot of cumulative incidence in diabetes remission after the indicated treatments. Closed circles and solid lines: Mice treated with CXCL10 DNA vaccination plus CFA injection. Open circles and solid lines: Mice treated with control DNA vaccination plus CFA injection. Closed triangles and dotted lines: Mice treated with CXCL10 DNA vaccination alone. * p < 0.05 by the log-rank test.