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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Cell Signal. 2010 Dec 23;23(5):772–777. doi: 10.1016/j.cellsig.2010.12.004

Fig. 2.

Fig. 2

NF-κB activation potential of TRAF-C mutants of TRAF6. (A) Relative activity of a NF-κB-responsive luciferase reporter in response to expression of FLAG-tagged wild type or the indicated TRAF6 mutants in HEK293T cells. The results are the means ± SE of relative luciferase activity from at least three independent experiments. The asterisks designate the TRAF6 mutants that show a statistically significant difference in their ability to activate NF – κB relative to wild type TRAF6. (B) Representative Western blots showing the expression of FLAG-tagged wild type or mutated TRAF6 isoforms and β-actin in cell lysates analyzed in A.