. Author manuscript; available in PMC: 2011 Apr 1.

Published in final edited form as: Childs Nerv Syst. 2010 Jul 13;26(10):1263–1273. doi: 10.1007/s00381-010-1208-9

Table.

Thrombophilia Evaluation for Pediatric Arterial Ischemic Stroke

Tests^*
Complete blood count

Prothrombin time (or international normalized ratio)

Activated partial thromboplastin time (APTT)

Prothrombin gene mutation 20210A
Activated protein C resistance

Factor V Leiden G1691A gene testing

Antiphospholipid antibody testing including:
Dilute Russell’s viper venom time
Beta 2 glycoprotein IgG and IgM
Anticardiolipin antibodies IgG and IgM

Lipoprotein (a)

Protein C activity

Protein S activity

Antithrombin III activity

Fasting homocysteine

Sickle cell screen or hemoglobin electrophoresis^†

There is not good evidence for this evaluation. This list is a compilation of tests sent at our institutions and supported by literature and expert opinion. [17, 18, 33, 84, 85].

^†

If not sent as part of the newborn screen.