Figure 5.

a: Western blotting for ERK activation of nHDF in constructs formed and stretched on FlexCell membranes. Treatment conditions were with and without TGF-β1 and p38 inhibitor SB203580, with and without cyclic stretching at 10% strain amplitude and 0.5 Hz. b: Ratio of pERK/tERK under cyclic stretching at 1 hour normalized to the same treatment with static incubation. c: Ratio of pERK/tERK under cyclic stretching at 1 week normalized to the same treatment with static incubation. d: Ratio of Collagen/Cell concentrations after 1 week.