Table 1. Kinetic and thermodynamic parameters for the wild-type and SH3 variants.

Protein	K d (µM)	T m (K)	ΔH m (kJ/mol)
Wild-type	2.30±0.47	345.2±0.5	195.9±13.5
N17	0.55±0.07	312.9±0.7	122.8±9.0
N47	0.53±0.09	306.6±1.8	88.7±10.6
R1	0.70±0.11	304.5±1.6	92.6±9.4
R12	0.74±0.13	309.7±6.2	73.4±23.9
R13	0.44±0.07	330.8±0.5	123.8±6.0