Table 1. Genes ≥ 4-fold differentially expressed in colonic epithelium of untreated conventional and antibiotic treated mice.
Gene symbol | Product | Function[Reference] | Conventional/Antibiotic treated |
Ang4 | Angiogenin, ribonuclease A family, member 4 | AMF[24] | 17.8 |
Pla2g2a | Phospholipase A2, group IIA | AMF[26], [34] | 14.4 |
Retnlb | Resistin like beta | AMF[25], [27], [40] | 8.8 |
Pla2g4c | Phospholipase A2, group IVC | AA metabolism?[41] | 8.6 |
Reg3g | Regenerating islet-derived 3 gamma | AMF[25], [28] | 7.6 |
Reg3b | Regenerating islet-derived 3 beta | AMF[25] | 5.1 |
Gsdmc2 | Gasdermin C2 | Unknown[42] | 4.1 |
… | … | … | … |
Casp14 | Caspase 14 | Proteinase?[43] | 0.23 |
Cyp4b1 | Cytochrome P450, family 4, subfamily b, polypeptide 1 | Metabolism of carcinogens?[44] | 0.16 |
AMF, antimicrobial factor. AA, arachidonic acid.