Figure 7. Model for the role of BRM in flowering regulation.

A) Under LD conditions in WT plants the photoperiod pathway overcomes the repression mediated by BRM upon CO, FT and SOC1 to promote flowering. In a brm mutant, the high levels of expression of CO, FT and SOC1 leads to an early flowering phenotype in spite of the increase in FLC expression. B) Under SD conditions in WT plants, the photoperiod pathway is not induced and flowering relies on the activation of SOC1 by the GAs pathway; however in brm plants, although FT and SOC1 are still slightly up-regulated in spite of the strong FLC expression, flowering is not induced indicating that there are other pathways (“?” in the scheme) that are also repressed by BRM.