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. Author manuscript; available in PMC: 2011 Mar 21.
Published in final edited form as: J Mol Biol. 2010 Jun 1;400(4):878–888. doi: 10.1016/j.jmb.2010.05.041

Fig. 2.

Fig. 2

Thioflavin T monitored kinetics of the FC≡N variants of IAPP compared to wild type, together with TEM images of the FC≡N variants collected at the end of the reaction. Red curves are FC≡N variants and the black curve is wild-type IAPP. (a and b) IAPP F15FC≡N, (c and d) IAPP F23FC≡N, (e and f) IAPP Y37FC≡N. The scale bar in the TEM images represents 100 nm. Final conditions were 32 μM peptide, 2% HFIP, and 20 mM Tris–HCl at pH 7.4 and 25 °C.