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. 2010 Dec 8;19(3):313–319. doi: 10.1038/ejhg.2010.209

Figure 2.

Figure 2

Hierarchical clustering of 45 differentially expressed miRNAs between different subtypes of the disease (5q− syndrome, low-risk MDS (RA, RARS and RCMD), RAEB-1, RAEB-2 and AML with MLD) (P<0.001). The binary logarithm of relative miRNA expression changes is expressed by a color gradient intensity scale, as shown at the top. Green color indicates downregulation, red color indicates upregulation of miRNA expression. Each column represents a separate sample and each row a single miRNA. Particular miRNA clusters are color-coded on the right side of the heatmap. N, control samples; miR*, complementary miRNA variants.