Figure 4.

Plots showing the correlation between the positions of the mutations and the first and second largest deviations in the mutants of the T-4 lysozyme (a) and myoglobin (b). All of the mutants tabulated in Appendix A are plotted. Most of the point mutations marked on the y axis are accompanied by mutations C54a and C97a in the case of the T-4 lysozyme and D122n in myoglobin, as shown in Appendix A. Residue positions showing the largest or the second-largest deviations in most of the mutants, 60 of 62 in the T-4 lysozyme and 52 of 54 in myoglobin, are marked on the x axis. These positions are 40, 77, and 113 in the T-4 lysozyme and 48 and 121 in myoglobin (see Appendix A, for details).