Table 2. Pyruvate oxidation and ATP production rates in skeletal muscle.
Substrate | Patient | Reference range |
---|---|---|
[1-14C]pyruvate+malate | 1.53a | 3.61–7.48a |
[1-14C]pyruvate+carnitine | 2.07a | 2.84–8.24a |
ATP+CrP from oxidation of pyruvate | 13b | 42–81b |
Abbreviations: ATP, adenosine triphosphate; CrP, phosphocreatine.
nmol CO2/hr mU citrate synthase.
nmol ATP/hr mU citrate synthase.