Table 1. Demographic, clinical, and endophenotypic characteristics of the autistic sample.
N | Mean/median | Range | |
---|---|---|---|
Age in years (mean±SEM): | N=306 | 9.18±0.33 | 2–33 |
Median VABS scores: | N=137 | ||
Communication | 69.0 | 19–128 | |
Daily living skills | 67.0 | 14–170 | |
Socialization | 66.0 | 25–140 | |
Motor skills | 80.0 | 25–128 | |
Composite | 60.0 | 19–137 | |
Head circumference: (median percentile±IQR/2) | N=265 | 82.5±23.75 | 2.5–98.5 |
Serotonin blood levels: (mean ng/ml±SEM) | N=158 | 329.5±20.9 | 31.0–987.1 |
Urinary oligopeptiduria: (mean μm2±SEM) | N=231 | 346.2±16.5 | 57–1213 |
N | Percent (%) | ||
Gender: | |||
Male | 269 | 87.9 | |
Female | 37 | 12.1 | |
M/F ratio | 7.3:1 | ||
Family type: | |||
Simplex | 281 | 95.9 | |
Multiplex | 12 | 4.1 | |
DSM-IV diagnosis: | |||
Autistic disorder | 207 | 67.6 | |
Asperger syndrome | 27 | 8.8 | |
PDD – NOS | 72 | 23.6 | |
IQ (N=71): | |||
>70 | 18 | 25.4 | |
<70 | 53 | 74.6 |
Abbreviations: IQR/2, semi-interquartilic range; PDD – NOS, pervasive developmental disorder – not otherwise specified.