Table 4. Association of ITGB3 and SLC6A4 genotypes with clinical variables.
| Clinical variable | Genotype | Statistics | ||
|---|---|---|---|---|
| ITGB3 rs12603582 | ||||
| Pregnancy duration | G/G | G/T | T/T | |
| At term | 60.9% (126) | 33.3% (69) | 5.8% (12) | χ2=9.78, 2 d.f., P=0.008 |
| Pre-term | 38.7% (12) | 61.3% (19) | 0.0% (0) | |
| ITGB3 rs5918 (Leu33Pro) | ||||
| Pain tolerance | T/T | C/T | C/C | |
| Normal | 60,3% (35) | 29.3% (17) | 10.4% (6) | χ2=6.98, 2 d.f., P=0.030 |
| Increased | 84.8% (28) | 15.2% (5) | 0.0% (0) | |
| Allergies in the patient | ||||
| Absent | 74.5% (117) | 24.2% (38) | 1.3% (2) | χ2=6.74, 2 d.f., P=0.034 |
| Present | 65.6% (42) | 26.6% (17) | 7.8% (5) | |
| Obstetric complications in the mother | ||||
| Absent | 76.7% (112) | 20.6 % (30) | 2.7% (4) | χ2=6.40, 2 d.f., P=0.041 |
| Present | 61.0% (47) | 32.5% (25) | 6.5% (5) | |
| SLC6A4 5-HTTLPR | ||||
| Food allergies in family members | S/S | S/L | L/L | |
| Absent | 29.0% (51) | 45.5% (80) | 25.6% (45) | χ2=10.98, 2 d.f., P=0.004 |
| Present | 15.8% (6) | 31.6% (12) | 52.6% (20) | |
| Increased pain tolerance | ||||
| Normal | 40.0% (28) | 35.7% (25) | 24.3% (17) | χ2=7.60, 2 d.f., P=0.022 |
| Increased | 20.0% (9) | 33.3% (15) | 46.7% (21) | |
| Autoimmune disease in first-degree relatives | ||||
| Absent | 28.7% (37) | 44.2% (57) | 27.1% (35) | χ2=6.05, 2 d.f., P=0.048 |
| Present | 20.0% (5) | 28.0% (7) | 52.0% (13) | |
| Immune and/or allergic disease in the family | ||||
| Absent | 28.0% (37) | 47.0% (62) | 25.0% (33) | χ2=4.98, 2 d.f., P=0.083 |
| Present | 23.8% (20) | 36.9% (31) | 39.3% (33) | |