Table 1.

Basic clinical and histopathological characteristics of patients with EOPCs and patients in control groups 1–2

Variable	Main study group: EOPCs (n = 23)	Control group 1: NENs of the pancreas in young patients (n = 13)	Control group 2: Ductal pancreatic adenocarcinomas in older patients (n = 39)
Gender (male/female)	13:10	7:6	23:16
Age (median, interquartile range)	42.0 (40.0–44.0)a	36.0 (35.0–44.0)a	60.0 (55.0–66.0)
Localization (head/body/tail/more than 1 segment/not known)	18:0:2:3:0	5:1:6:0:1	37:0:1:1:0
Tumor characteristics	21 cases of conventional ductal adenocarcinoma, a single case of undifferentiated carcinoma, a single case of invasive carcinoma associated with IPMN (colloid carcinoma)	12 cases of neuroendocrine tumors G1/G2, a single case of (poorly differentiated) neuroendocrine carcinoma	30 cases of conventional ductal adenocarcinoma, a single case of undifferentiated carcinoma, eight cases of invasive carcinoma associated with IPMN (six of tubular differentiation and two of colloid differentiation)

EOPC Early onset pancreatic cancer; NEN neuroendocrine neoplasm; IPMN intraductal papillary mucinous neoplasm

^aMedian age of patients with EOPCs versus median age of young patients with NENs, Mann–Whitney U test, p = 0.087