Table 3.

Multivariate analysis of disease-free and overall survival of patients treated with adjuvant chemotherapy (group B2 + C, n = 203)

Category	Disease-free survival		Overall survival
	Hazard ratio (95% Cl)	p	Hazard ratio (95% Cl)	p
Sex	1.20 (0.75–1.90)	0.44	1.42 (0.77–2.65)	0.27
Age	1.01 (0.99–1.03)	0.32	1.01 (0.98–1.04)	0.58
Astler–Coller	3.16 (1.86–5.36)	<0.0001	3.60 (1.77–7.33)	0.0004
Grade	1.48 (0.94–2.32)	0.09	1.95 (1.07–3.56)	0.03
Tumor site	0.64 (0.34–1.20)	0.17	0.62 (0.26–1.49)	0.28
P21WAF1	0.52 (0.33–0.83)	0.0062	0.36 (0.20–0.66)	0.0009