Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A) Gel shift assay for CAR. Pooled liver samples from at least 3 mice were used for preparing nuclear samples. P represents probe only, C represent cold probe (B) mRNA levels of CAR before and after TCPOBOP administration. Pooled liver samples from at least 3 mice were used for preparing RNA. (C) Real time PCR for UGT1A1. Levels were normalized relative to expression of cyclophillin in each sample. Fold change in gene expression was calculated by using the 2(−ΔΔCt) method.
