Figure 4.

Effect of PBMC and IL-1β stimulation on the immunosuppressive activity of hMSCs. Immunosuppressive activity (mean ± standard deviation; n = 10; 5 control and 5 FGF-treated) of medium conditioned by MSCs from different passages stimulated with PBMCs (black bars) or IL-1β (white bars). Values are expressed as percent inhibition relative to the internal controls. Higher bars indicate higher immunosuppressive activity. Asterisks indicate significant differences in one-tail paired t-test; *P < .05.