Table 2.

Effect of EESC and EAF on maximal electroshock induced seizures in mice

Group	Treatment	Dose	Duration of hind limb extensor phase (seconds)	% Mortality
I	Vehicle	1 mL	16.1 ± 0.75	72.33
II	Phenytoin	20 mg/kg	9.3 ± 0.7***	100**
III	EESC	100 mg/kg	13.66 ± 0.91a	94.33*
IV	EESC	200 mg/kg	12.83 ± 0.60**b	100**
V	EESC	400 mg/kg	11.30 ± 0.33***	100**
VI	EAF	100 mg/kg	12.33 ± 0.42**b	100**
VII	EAF	200 mg/kg	10.16 ± 0.70***b	100**
VIII	EAF	400 mg/kg	8.83 ± 0.30***	100**

EESC: Ethanolic extract of Smilax china Linn.; EAF: Ethyl acetate fraction; Values are mean ± SEM (n =6). Statistical significance was determined by ANOVA, followed by Dunnett’s “t” test (n=6);

^***P < 0.001,

^**P < 0.01,

^*P < 0.05 when compared against control

^aP < 0.001,

^bP < 0.01,

when compared against standard