Table 3.
Effect of N. alba extract on behavior of mice in light and dark test
| Treatment (mg/kg, p.o.) | Time spent in lighted box (sec) | Time spent in dark box (sec) | No. of crossings | Duration of immobility (sec) |
|---|---|---|---|---|
| Vehicle | 119.2 ± 12.83 | 209.0 ± 19.93 | 16.83 ± 1.53 | 37.17 ± 3.74 |
| Diazepam (1) | 198.2 ± 12.64c | 117.8 ± 10.42c | 26.50 ± 3.212a | 21.00 ± 2.95b |
| N. alba extract (100) | 229.8 ± 16.39c | 139.2 ± 8.57b | 28.67 ± 2.71b | 23.67 ± 1.83a |
| N. alba extract (200) | 253.0 ± 7.34c | 144.5 ± 4.68b | 27.50 ± 1.31a | 26.17 ± 3.26a |
Values represent mean ± SEM (n = 6);
a
P < 0.05;
b
P < 0.01;
c
P < 0.001 vs.
vehicle-treated control group (one-way ANOVA followed by Dunnett’s “t” test)