Table 3.
Effect of EGA on lipid profile in STZ-induced diabetes rats
| Group | Treatment | HDL-cholesterol (mg/dl) | Total cholesterol (mg/dl) | Triglycerides (mg/dl) | LDL cholesterol (mg/dl) |
|---|---|---|---|---|---|
| Normal control | 0.5% NaCMC | 35.18 ± 197 | 115.87 ± 6.87 | 81.92 ± 4.22 | 64.31 ± 2.64 |
| Diabetic control | 0.5% NaCMC | 21.44 ± 1.73# | 216.82 ± 6.99# | 174.93 ± 5.70# | 160.40 ± 3.45# |
| EGA | 250 mg/kg | 27.316 ± 1.12 | 175.32 ± 6.24** | 138.82 ± 5.03** | 120.24 ± 3.52** |
| EGA | 500 mg/kg | 33.53 ± 2.66** | 153.63 ± 4.36** | 102.80 ± 5.62** | 99.54 ± 3.03** |
| EGA | 1000 mg/kg | 34.49 ± 1.57** | 138.78 ± 7.59** | 83.32 ± 6.33** | 87.62 ± 2.07** |
| Metformin | 500 mg/kg | 33.10 ± 1.81** | 146.88 ± 5.02** | 96.15 ± 3.84** | 94.55 ± 0.87** |
Values are expressed as mean ± SEM; n = 6; *P < 0.05;
**
P < 0.01 vs. diabetic control group
#
P < 0.05 vs. normal control group; one-way ANOVA followed by Dunnett’s multiple comparisons test; EGA, aqueous extract of Elaeocarpus ganitrus