Figure 4.

Proteomic definition of MSCs—proposal for the protein inventory. The main aspects for a proteomic definition of MSCs include (i) the expression of a specific cell surface markers, (ii) the reactiveness to growth factors, (iii) the re-activation of developmental pathways, (iv) the interaction with the extracellular matrix, (v) the regulation of transcription and translation, (vi) the regulation of cell number, and (vii) the machinery for resistance to cellular stress (modified from [6, 51]).