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. 2011 Apr;17(4):718–727. doi: 10.1261/rna.2540311

FIGURE 1.

FIGURE 1.

PUF protein–RNA interaction. (A) Hs PUM1: structure of human Pumilio1–RNA complex (PDB accession code 1M8Y) (Wang et al. 2002). (B) Ce FBF-2: structure of C. elegans FBF-2–RNA complex (PDB accession code 3K5Y) (Wang et al. 2009b). Eight RNA-recognition helices (gray in structures and diagrams) contribute side chains to contact RNA bases (blue). (Red) Stacking residues; interactions with base edges are not shown. (Beige shading) Amino acid side chains and RNA bases involved in stacking interactions. (C) Key interactions in the FBF-2–RNA complex. (Red) Stacking residues; (green) base edge interacting residues; (blue) RNA bases.