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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Ann N Y Acad Sci. 2010 Oct;1207(Suppl 1):E7–15. doi: 10.1111/j.1749-6632.2010.05714.x

Figure 3.

Figure 3

Immunostaining of the cornea of a LeCre;svegfr-2loxP/loxP newborn mouse, which selectively lacks svegfr-2 in the cornea. A) CD31, a pan-endothelial cell marker is stained red corneal vessels. B) A specific marker for lymphatic endothelial cells, Lyve-1 (lymphatic vascular endothelial hyaluronan receptor-1) stains corneal lymphatics in green. C) Merged image of CD31 and Lyve-1 staining demonstrates that all vessels within the cornea are lymphatic vessels, whereas in the limbus both types of vessels are present. The arrows point to typical blind-ended morphology of lymphatic vessels.