Table 1.

Average rat body temperature, arterial P_O2, arterial P_CO2, mean arterial blood pressure (MAP), apneic threshold and recruitment threshold before and 60 min following reduced respiratory neural activity with hypocapnia, isoflurane or high frequency ventilation (HFV). Values are also included for an equivalent duration in control rats not receiving reduced respiratory neural activity (time controls and vagotomized rats receiving HFV). MAP was significantly lower than baseline at 60 min following isoflurane. No other time-dependent changes were observed in any group.

		Temp	PaO2	PaCO2	MAP	Apneic threshold	Recruitment threshold
hypocapnia	baseline	36.6 ± 0.1	272 ± 4	43.0 ± 0.7	126 ± 2	37.9 ± 1.0	41.6 ± 0.8
	60 min	36.7 ± 0.1	266 ± 5	43.2 ± 0.7	122 ± 3
isoflurane	baseline	37.2 ± 0.1	274 ± 7	47.1 ± 1.7	127 ± 4	36.7 ± 2.1	45.2 ± 1.4
	60 min	37.2 ± 0.1	270 ± 5	47.7 ± 1.7	106 ± 7*
HFV	baseline	37.2 ± 0.1	234 ± 6	48.6 ± 0.7	120 ± 3	44.3 ± 0.5	46.6 ± 0.5
	60 min	37.3 ± 0.1	238 ± 5	48.3 ± 0.6	124 ± 5
HFV vagotomized	baseline	37.3 ± 0.2	229 ± 5	45.6 ± 0.8	114 ± 4	39.7 ± 0.4	42.4 ± 0.4
	60 min	37.4 ± 0.2	238 ± 5	45.2 ± 0.6	108 ± 2
Time control	baseline	37.0 ± 0.2	249 ± 8	44.8 ± 1.4	126 ± 4	41.2 ± 1.3	44.0 ± 1.2
	60 min	36.9 ± 0.2	249 ± 6	44.6 ± 1.3	126 ± 3

^*significantly different than baseline; p<0.05