Skip to main content
. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Semin Radiat Oncol. 2011 Apr;21(2):80–87. doi: 10.1016/j.semradonc.2010.10.003

Figure 2.

Figure 2

(A) The principle of multivalency. Antibodies are bivalent while small peptides or small molecules are mono-valent. A particle with multiple targeting moieties provides multiple binding sides and is multivalent. Multivalency increases the validity to the target considerably. (B) A mono-modal imaging agent is suitable to be detected with one modality; a multimodal agent can be detected with several imaging modalities as it contains several different labels. This allows to combine the advantages of various modalities in one particle.