Figure 6. MitoPLD is required for mitochondrial localization.
A. Mitochondria are mislocalized around the centrosome and colocalize with TDRD1 in MitoPLD-/- testes. Prospermatogonia from E16.5 testes were double-stained with MitoTracker and TDRD1 antibody.
B. Conglomeration of mitochondria around the nucleus and dininished pi-body formation in MitoPLD-/- prospermatogonia observed by electron microscopy. Sections from E16.5 testes were studied. Mitochondria are indicated by arrows and pi-bodies in the control testes are indicated by arrowheads. Nuclei are marked āNā in the left and middle panels.