Figure 4.

Analysis of TRPC3-deficient mice (Hartmann et al. 2008). (A) Slow EPSC in a wild-type mouse (lower trace) and the corresponding local dendritic Ca²⁺ response (upper trace). (B) Similar recording in a TRPC3^−/− mouse. (C) Summary graphs for normalized (to stimulation strength) slow EPSCs and Ca²⁺ transients. (D) DHPG evoked a slow inward current (lower trace) and a local Ca²⁺ transient (upper trace) in a wild-type mouse. (E) Similar recording in a TRPC3^−/− mouse. (F) Summary of DHPG-evoked current (right) and Ca²⁺ (left) responses.