TABLE 1.
Characteristics of groups with neuropsychological assessment and magnetic resonance spectroscopy subset
| NP assessment |
MRS subset |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| HIV+TBI+ (N = 110) | HIV+TBI− (N = 590) | t value or x2 | p value | HIV+TBI+ (N = 17) | HIV+TBI− (N = 84) | t value or χ2 | p value | ||
| Age (years) | 43.6(8.4) | 43.6(8.0) | −0.13 | .45 | 47.5(6.3) | 47.1(5.9) | −0.25 | .80 | |
| Education (years) | 12.3(2.8) | 12.6(2.3) | 1.19 | .88 | 13.2(3.2) | 13.1(2.1) | −0.15 | .88 | |
| WRAT-3 Reading | 91.5(17.3) | 90.7(16.7) | −0.47 | .32 | 96.1(15.9) | 93.5(15.7) | −0.61 | .54 | |
| Sex (% male) | 89.2 | 74.9 | 12.10 | .001 | 100.0 | 84.5 | 5.17 | .08 | |
| Ethnicity (% non-White) | 56.4 | 59.5 | 0.37 | .54 | 58.8 | 57.1 | 0.02 | .90 | |
| No. of ARVs | 2.2(1.5) | 2.1(1.6) | −0.55 | .29 | 2.3(1.6) | 2.4(1.5) | 0.37 | .71 | |
| ARV history (% currently using) | 69.1 | 65.6 | 0.51 | .47 | 70.6 | 75.0 | 0.14 | .70 | |
| % on HAART | 69.1 | 64.4 | 0.91 | .34 | 70.6 | 73.8 | 0.07 | .78 | |
| Nadir CD4 | 213.3(188.5) | 219.9(210.7) | 0.31 | .62 | 215.2(212.4) | 174.5(152.6) | −0.93 | .35 | |
| % AIDSa | 60.0 | 61.5 | 0.08 | .77 | 64.7 | 70.2 | 0.20 | .65 | |
| Plasma HIVb (% detectable) | 65.1 | 70.7 | 1.31 | .25 | 47.1 | 44.6 | 0.04 | .85 | |
| CSF HIVb (% detectable) | 37.4 | 38.6 | 0.05 | .83 | 37.5 | 29.5 | 0.39 | .53 | |
| % HCV seropositive | 33.3 | 31.8 | 0.10 | .75 | 41.2 | 33.3 | 0.38 | .54 | |
Note. For t value or χ2: Variables with standard deviations have a t value; variables with % values have a χ2 value. NP = neuropsychological. MRS = magnetic resonance spectroscopy. WRAT-3 = Wide Range Achievement Test-Third Edition. ARV = antiretroviral. HAART = highly active antiretroviral therapy. CSF = cerebrospinal fluid. HCV = hepatitis C virus. Standard deviations in parentheses. aBased on 1993 Centers for Disease Control (CDC) classification (Centers for Disease Control, 1992). bBased on limit of detection = 50 copies.