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. 2011 Jan 1;7(1):115–119. doi: 10.4161/hv.7.1.13740

Table 1.

2009–2010 H1N1 influenza pandemic timeline

H1N1 influenza timeline H1N1 Vaccine timeline
2009
  • CDC: respiratory samples from 3 children unsubtypable influenza A

  • First “swine” flu-attributable death occurs (Oaxaca, Mexico)

April
  • >10,000 cases reported worldwide

  • >98% of probable influenza cases testing positive for 2009 H1N1

  • 2009 H1N1 virus isolated and identified as novel

May
  • Vaccine development begins

  • WHO declares pandemic (June 11)

June
  • Planning for vaccine distribution and administration

July
  • Ongoing vaccine development, testing, production & planning for rollout

August
  • NIH initiates clinical trials to determine vaccine safety and immunogenicity

  • ACIP releases recommendations for vaccine prioritization

September
  • 4 vaccines against 2009 H1N1 influenza approved by FDA

  • Healthy adults and older children found to need 1 dose of vaccine to generate strong immune response; children under 9 need two doses

  • Influenza activity peaks the second week of the month

October
  • 3 million doses of nasal spray are the first vaccine ready for distribution

  • 14.1 million doses are available by the end of October

  • CDC estimates H1N1 deaths among children and teens >500

  • Flu activity begins to decline late in the month

November
  • FDA approves a 5th vaccine against 2009 H1N1 influenza

  • FDA authorizes an additional vaccine for use among infants and children

  • 1 dose of vaccine is found to elicit a strong immune response among pregnant women

  • >61 million doses of vaccine available by the end of the month

  • The number of states reporting widespread flu activity continues to decline

December
  • >93 million doses of vaccine are available

  • Vaccination efforts expanded to the general public

2010
January
February
  • FDA and WHO recommend that 2009 H1N1 be included in the 2010–2011 seasonal influenza vaccine

  • ACIP recommends that all people >6 months of age receive yearly seasonal influenza vaccination

  • Early vaccine expiration dates approaching

March
  • Increased number of cases and hospitalizations in the southeastern United States

April
  • >80 million people vaccinated

May
  • Southern Hemisphere reports of influenza A H3N2 and Northern Hemisphere reports of influenza B viral circulation exceed cases of 2009 H1N1

June
July
  • WHO cancels pandemic declaration (August 10)

August