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. 2010 Oct-Dec;1(4):328–334. doi: 10.4161/self.1.4.13315

Table 1.

Peptide sharing between bacterial proteomes and the human proteome at the 5-, 6-, 7- and 8-mer level

Taxa Id Bacterium name 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16
299768 Streptococcus thermophilus 450402 3863966 35961 92.8 448812 345526 33679 31.8 447222 29009 13533 3.5 445632 5821 2258 0.5
367928 Bifidobacterium adolescentis 593219 4720571 35984 91.6 591592 464558 34565 31.8 589965 41915 16817 3.6 588338 7312 3025 0.4
206672 Bifidobacterium longum 631639 4930744 35983 91.7 629916 507033 34673 32.5 628193 46282 17784 3.7 626470 7796 3266 0.4
257314 Lactobacillus johnsonii 580247 4373499 35966 91.6 578438 394509 34122 29.9 576629 32622 14862 3.2 574820 5814 2354 0.4
272621 Lactobacillus acidophilus 576525 4285917 35956 91.4 574666 378992 33885 29.0 572807 31372 14409 3.0 570948 5704 2190 0.4
203120 Leuconostoc mesenteroides 598355 4551589 35963 92.0 596353 419771 34303 30.4 594351 34970 15491 3.3 592349 6662 2432 0.5
416870 Lactococcus lactis 672683 4980061 35981 92.1 670299 495503 34595 31.5 667915 41383 17246 3.5 665531 6919 2831 0.4
393595 Alcanivorax borkumensis 896972 6304479 35999 91.5 894220 736390 35320 33.5 891468 62704 21456 4.1 888716 9487 4176 0.5
220668 Lactobacillus plantarum 904305 5835444 35989 90.8 901306 623037 35071 30.0 898307 52498 19685 3.3 895308 8195 3575 0.4
226185 Enterococcus faecalis 940332 6145880 35988 91.6 937095 668944 35158 31.1 933858 57666 20168 3.3 930621 9470 3796 0.4
420662 Methylibium petroleiphilum 1363510 7268505 36004 91.3 1359155 1153424 35558 35.9 1354800 123368 26348 5.1 1350445 19643 7555 0.7
251221 Gloeobacter violaceus 1359892 7559021 36004 91.7 1355488 1155772 35593 35.8 1351084 114279 26125 4.7 1346680 18514 7090 0.5
369723 Salinispora tropica 1499556 7020220 35995 91.6 1495034 1268110 35537 37.5 1490512 142761 27415 5.5 1485990 20474 8513 0.6
78245 Xanthobacter autotrophicus 1598054 7692783 36005 91.6 1593085 1285165 35609 35.8 1588116 136687 27146 4.9 1583147 21199 7980 0.6
138119 Desulfuobacterium hafniense 1580893 8351354 36000 90.5 1575878 1125244 35636 31.4 1570863 97706 25570 3.5 1565848 14124 6018 0.4
318586 Paracoccus denitrificans 1541153 7483126 35998 90.8 1536137 1192734 35649 34.5 1531121 122240 26532 4.7 1526105 17463 7217 0.6
351746 Pseudomonas putida 1734619 8415989 36006 90.5 1729375 1327148 35661 33.9 1724131 126059 27425 4.3 1718887 16807 7352 0.5
222523 Bacillus cereus 1505863 7776742 36005 90.0 1499864 981068 35501 29.7 1493866 82158 23724 3.2 1487873 10991 4881 0.4
366394 Sinorhizobium medicae 1896855 8634389 36006 90.6 1890710 1395567 35700 33.6 1884565 133621 27663 4.2 1878420 20378 7549 0.5
224911 Bradyrhizobium japonicum 2582736 9728471 36007 89.8 2574488 1816906 35804 32.9 2566240 183683 29933 4.1 2557992 27201 9643 0.5
471472 Chlamydia trachomatis 306365 3176212 35959 93.3 305482 276387 33051 34.4 304599 22712 11834 4.1 303716 3440 1592 0.5
455434 Treponema pallidum 345928 3356569 35952 93.0 344863 299569 33510 33.8 343798 26743 12789 3.9 342733 5561 2064 0.5
392021 Rickettsia rickeitsii 313106 2762374 35941 92.6 311761 226202 31809 30.7 310416 21699 10218 3.6 309071 5559 1605 0.7
458234 Frunciselia tularensis 450826 3551140 35966 91.8 449318 298668 33231 29.6 447810 24243 12135 3.2 446302 4463 1687 0.5
85962 Helicobacter pylori 485536 3780814 35963 92.2 483971 359383 33668 31.3 482406 29876 13919 3.5 480841 4281 1925 0.4
224326 Borrelia burgdorferi 412046 2867951 35918 93.1 410464 257661 32030 30.8 408882 20885 11291 3.3 407300 3026 1426 0.4
195099 Campylobacter jejuni 531256 3866438 35955 92.2 529420 374675 33686 30.7 527584 30421 14358 3.4 525748 5188 2141 0.4
374833 Neisseria meningitidis 559567 4473458 35977 92.2 557569 433384 34379 32.4 555571 38343 16154 3.8 553573 6201 2582 0.6
516950 Streptococcus pneumoniae 624663 4783135 35976 92.2 622474 467024 34432 31.7 620285 38722 16550 3.5 618096 6560 2702 0.4
257309 Corynebacterium diphtheriae 716248 5461966 35986 92.2 713983 601188 34952 34.0 711718 51983 19542 4.0 709453 7482 3527 0.5
212717 Clostridium tetani 799625 4942017 35972 91.3 797211 519578 34461 29.5 794797 42607 17049 3.1 792383 6520 2876 0.4
273036 Staphylococcus aureus 725020 4995196 35982 91.2 722512 465501 34460 28.8 720004 36783 16275 3.0 717496 5780 2508 0.4
262698 Brucella abortus 874969 6056419 35991 92.0 871895 714382 35165 33.8 868821 65769 21087 4.2 865747 12203 4314 0.7
400673 Legionella pneumophila 1021398 6572966 35999 90.7 1018194 703289 35287 30.2 1014990 57003 20586 3.3 1011786 9586 3736 0.4
520 Bordetella pertussis 1051997 6271766 35998 91.6 1048737 884648 35324 35.3 1045477 91024 23660 4.9 1042217 14756 5916 0.7
243277 Vibrio cholerae 1138797 7077244 36000 90.7 1134997 833801 35408 31.2 1131197 70647 22617 3.5 1127398 12337 4680 0.4
349746 Yersinia pestis 1123279 7065400 36001 90.8 1119462 846102 35433 31.9 1115645 73246 22780 3.7 1111828 11446 4709 0.5
83331 Mycobacterium tuberculosis 1307195 6877511 35993 91.5 1302949 1082521 35477 35.8 1298704 115970 25679 4.9 1294460 19203 7141 0.6
99287 Salmonella typhimurium 1401436 7838576 36001 90.0 1396908 1015124 35570 31.4 1392380 89038 24671 3.6 1387852 12184 5316 0.4
261594 Bacillus anthracis 1439159 7615447 36005 90.1 1433570 944793 35483 29.7 1427981 76954 23306 3.2 1422392 11356 4851 0.4
Total bacterial overlap*: 15260383 36014 9133718 36014 1643139 35906 200708 31170

The level of peptide overlap between 40 bacterial proteomes and the human proteome is shown. The filtered bacterial proteomes consisted of 128,248 unique proteins, while the human proteome contained 36,014 proteins at the time of the analysis. Bacteria that are pathogenic to humans are shown in bold. Information for each bacterium can be found at ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi. Column details are as follows: (1) Number of 5-mer occurrences in the bacterial proteome (including duplicate instances of same unique 5-mer); (2) Observed bacterial 5-mer occurrences in the human proteome (including multiple occurrences); (3) Number of human proteins involved in the pentapeptide overlap; (4) Percent of unique bacterial 5-mers which occur in the human proteome; (5) Number of 6-mer occurrences in the bacterial proteome (including duplicate instances of same unique 6-mer); (6) Observed bacterial 6-mer occurrences in the human proteome (including multiple occurrences); (7) Number of human proteins involved in the hexapeptide overlap; (8) Percent of unique bacterial 6-mers which occur in the human proteome; (9) Number of 7-mer occurrences in the bacterial proteome (including duplicate instances of same unique7-mer); (10) Observed bacterial 7-mer occurrences in the human proteome (including multiple occurrences); (11) Number of human proteins involved in the heptapeptide overlap; (12) Percent of unique bacterial 7-mers which occur in the human proteome; (13) Number of 8-mer occurrences in the bacterial proteome (including duplicate instances of same unique 8-mer); (14) Observed bacterial 8-mer occurrences in the human proteome (including multiple occurrences); (15) Number of human proteins involved in the octapeptide overlap; (16) Percent of unique bacterial 8-mers which occur in the human proteome.

*

Obtained by combining all bacterial proteomes into one protein set, and computing the overlap of this set with the human proteome. The human proteome was downloaded from UniProtKB23 and analyzed by custom programs written in C24 (see under Methods).