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. 2011 Apr 15;138(8):1595–1605. doi: 10.1242/dev.052787

Fig. 6.

Fig. 6.

Phenotypic rescue of MB defects by transgenic expression of NRG-180, but not NRG-167. (A) Scheme of NRG-180 protein structure. (B-E) Anti-Fasciclin 2 (1D4) staining of pharate adult brains. (B) yw control with normal MB morphology. Scale bar: 50 μm. (C) Nrg3/−;;; OK107/+ with αβ axon stalling phenotype (γ lobes not shown). (D) Rescue of peduncle formation and partial rescue of lobe structure in Nrg3/−;; UASNrg-167/+; OK107/+ brains. (E) Full rescue in Nrg3/−; UASNrg-180/+;; OK107/+ displaying wild-type MB morphology. (F) Summary of αβ axon phenotypes listing percentages of brains with the relevant phenotype. n is the number of brain hemispheres analyzed.