Table 1.
Early treatment group (N = 45) | Control group (N = 45) | P value | |
---|---|---|---|
Male (%) | 34/45 (75.6%) | 32/45 (71.1%) | 0.64† |
Age, mean in years ± SD | 25.7 ± 10.0 | 25.5 ± 9.8 | 0.93‡ |
BMI, median in kg/m2 (IQR) | 21.3 (19.4–24.7) | 22.3 (20.7–24.0) | 0.67§ |
No. (%) with 1 lesion | 34 (75.6%) | 34 (75.6%) | |
No. (%) with 2 lesions | 7 (16.7%) | 8 (17.8%) | |
No. (%) with 3 lesions | 4 (8.9%) | 3 (6.7%) | |
Lesion size,¶ median (IQR), mm2 | 180 (70–400) | 198 (100–400) | 0.78§ |
No (%) helminth | |||
Mean egg count/gm stool (range) | |||
Hookworm | 43/45 (95.6%) | 38/45 (84.4%) | 0.079† |
400 [24–1920] | 423 [24–2332] | ||
Trichiura trichuris | 30/45 (66.7%) | 15/45 (33.3%) | 0.0016† |
324 [24–840] | 361 [24–2424] | ||
Ascaris lumbricoides | 31/45 (68.9%) | 25/45 (55.6%) | 0.019† |
9786 [24–42,428] | 10,803 [24–48,404] | ||
Strongyloides stercoralis | 2/45 (4.4%) | 3/45 (6.7%) | 1.00‖ |
Schistosoma mansoni | 6/45 (13.3%) | 7/45 (15.6%) | 0.76† |
276 [24–768] | 124 [24–288] | ||
Time to cure, median (IQR), days | 98 (64–138) | 88 (56–126) | 0.13** |
BMI = body mass index; IQR = interquartile range; SD = standard deviation.
χ2 test.
Student's t test.
Wilcoxon rank-sum test.
The lesion with the greatest area at presentation was considered to be the main lesion.
Fisher's exact test.
Log-rank test.